National Center for Biotechnology InformationU. The squamocolumnar junction is the area most commonly affected by HPV and where many of the lesions are likely to arise. Information about ongoing clinical trials is available from the NCI website. Selected tumors are also suitable for interstitial radiation therapy. Local excision can be considered for small well-differentiated carcinomas of the anal margin. Scaly, erythematous, sometimes pigmented; often associated with condylomas in younger patients. Pop-up div Successfully Displayed This div only appears when the trigger link is hovered over.
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